• 2nd PRESTIGIO Registry meetING on HIV multidrug resistance

2nd PRESTIGIO Registry meetING on HIV multidrug resistance

2nd PRESTIGIO Registry meetING on HIV multidrug resistance

Faculty | Today, most people living with HIV (PLWH) with access to ART successfully achieve virological suppression,  although drug resistance is still an unsolved problem that may dramatically reduce therapeutic options for this population. Faculty | Today, most people living with HIV (PLWH) with access to ART successfully achieve virological suppression,  although drug resistance is still an unsolved problem that may dramatically reduce therapeutic options for this population. Faculty | Today, most people living with HIV (PLWH) with access to ART successfully achieve virological suppression,  although drug resistance is still an unsolved problem that may dramatically reduce therapeutic options for this population. Faculty | Today, most people living with HIV (PLWH) with access to ART successfully achieve virological suppression,  although drug resistance is still an unsolved problem that may dramatically reduce therapeutic options for this population. Faculty | Today, most people living with HIV (PLWH) with access to ART successfully achieve virological suppression,  although drug resistance is still an unsolved problem that may dramatically reduce therapeutic options for this population. Faculty | Today, most people living with HIV (PLWH) with access to ART successfully achieve virological suppression,  although drug resistance is still an unsolved problem that may dramatically reduce therapeutic options for this population. Faculty | Today, most people living with HIV (PLWH) with access to ART successfully achieve virological suppression,  although drug resistance is still an unsolved problem that may dramatically reduce therapeutic options for this population. Faculty | Today, most people living with HIV (PLWH) with access to ART successfully achieve virological suppression,  although drug resistance is still an unsolved problem that may dramatically reduce therapeutic options for this population. Faculty | Today, most people living with HIV (PLWH) with access to ART successfully achieve virological suppression,  although drug resistance is still an unsolved problem that may dramatically reduce therapeutic options for this population. Faculty | Today, most people living with HIV (PLWH) with access to ART successfully achieve virological suppression,  although drug resistance is still an unsolved problem that may dramatically reduce therapeutic options for this population.

Faculty | Today, most people living with HIV (PLWH) with access to ART successfully achieve virological suppression,  although drug resistance is still an unsolved problem that may dramatically reduce therapeutic options for this population. Faculty | Today, most people living with HIV (PLWH) with access to ART successfully achieve virological suppression,  although drug resistance is still an unsolved problem that may dramatically reduce therapeutic options for this population. Faculty | Today, most people living with HIV (PLWH) with access to ART successfully achieve virological suppression,  although drug resistance is still an unsolved problem that may dramatically reduce therapeutic options for this population. Faculty | Today, most people living with HIV (PLWH) with access to ART successfully achieve virological suppression,  although drug resistance is still an unsolved problem that may dramatically reduce therapeutic options for this population. Faculty | Today, most people living with HIV (PLWH) with access to ART successfully achieve virological suppression,  although drug resistance is still an unsolved problem that may dramatically reduce therapeutic options for this population. Faculty | Today, most people living with HIV (PLWH) with access to ART successfully achieve virological suppression,  although drug resistance is still an unsolved problem that may dramatically reduce therapeutic options for this population. Faculty | Today, most people living with HIV (PLWH) with access to ART successfully achieve virological suppression,  although drug resistance is still an unsolved problem that may dramatically reduce therapeutic options for this population. Faculty | Today, most people living with HIV (PLWH) with access to ART successfully achieve virological suppression,  although drug resistance is still an unsolved problem that may dramatically reduce therapeutic options for this population. Faculty | Today, most people living with HIV (PLWH) with access to ART successfully achieve virological suppression,  although drug resistance is still an unsolved problem that may dramatically reduce therapeutic options for this population. Faculty | Today, most people living with HIV (PLWH) with access to ART successfully achieve virological suppression,  although drug resistance is still an unsolved problem that may dramatically reduce therapeutic options for this population.

Faculty | Today, most people living with HIV (PLWH) with access to ART successfully achieve virological suppression,  although drug resistance is still an unsolved problem that may dramatically reduce therapeutic options for this population. Faculty | Today, most people living with HIV (PLWH) with access to ART successfully achieve virological suppression,  although drug resistance is still an unsolved problem that may dramatically reduce therapeutic options for this population. Faculty | Today, most people living with HIV (PLWH) with access to ART successfully achieve virological suppression,  although drug resistance is still an unsolved problem that may dramatically reduce therapeutic options for this population. Faculty | Today, most people living with HIV (PLWH) with access to ART successfully achieve virological suppression,  although drug resistance is still an unsolved problem that may dramatically reduce therapeutic options for this population. Faculty | Today, most people living with HIV (PLWH) with access to ART successfully achieve virological suppression,  although drug resistance is still an unsolved problem that may dramatically reduce therapeutic options for this population. Faculty | Today, most people living with HIV (PLWH) with access to ART successfully achieve virological suppression,  although drug resistance is still an unsolved problem that may dramatically reduce therapeutic options for this population. Faculty | Today, most people living with HIV (PLWH) with access to ART successfully achieve virological suppression,  although drug resistance is still an unsolved problem that may dramatically reduce therapeutic options for this population. Faculty | Today, most people living with HIV (PLWH) with access to ART successfully achieve virological suppression,  although drug resistance is still an unsolved problem that may dramatically reduce therapeutic options for this population. Faculty | Today, most people living with HIV (PLWH) with access to ART successfully achieve virological suppression,  although drug resistance is still an unsolved problem that may dramatically reduce therapeutic options for this population. Faculty | Today, most people living with HIV (PLWH) with access to ART successfully achieve virological suppression,  although drug resistance is still an unsolved problem that may dramatically reduce therapeutic options for this population.

Faculty | Today, most people living with HIV (PLWH) with access to ART successfully achieve virological suppression,  although drug resistance is still an unsolved problem that may dramatically reduce therapeutic options for this population. Faculty | Today, most people living with HIV (PLWH) with access to ART successfully achieve virological suppression,  although drug resistance is still an unsolved problem that may dramatically reduce therapeutic options for this population. Faculty | Today, most people living with HIV (PLWH) with access to ART successfully achieve virological suppression,  although drug resistance is still an unsolved problem that may dramatically reduce therapeutic options for this population. Faculty | Today, most people living with HIV (PLWH) with access to ART successfully achieve virological suppression,  although drug resistance is still an unsolved problem that may dramatically reduce therapeutic options for this population. Faculty | Today, most people living with HIV (PLWH) with access to ART successfully achieve virological suppression,  although drug resistance is still an unsolved problem that may dramatically reduce therapeutic options for this population. Faculty | Today, most people living with HIV (PLWH) with access to ART successfully achieve virological suppression,  although drug resistance is still an unsolved problem that may dramatically reduce therapeutic options for this population. Faculty | Today, most people living with HIV (PLWH) with access to ART successfully achieve virological suppression,  although drug resistance is still an unsolved problem that may dramatically reduce therapeutic options for this population. Faculty | Today, most people living with HIV (PLWH) with access to ART successfully achieve virological suppression,  although drug resistance is still an unsolved problem that may dramatically reduce therapeutic options for this population. Faculty | Today, most people living with HIV (PLWH) with access to ART successfully achieve virological suppression,  although drug resistance is still an unsolved problem that may dramatically reduce therapeutic options for this population. Faculty | Today, most people living with HIV (PLWH) with access to ART successfully achieve virological suppression,  although drug resistance is still an unsolved problem that may dramatically reduce therapeutic options for this population.

Faculty | Today, most people living with HIV (PLWH) with access to ART successfully achieve virological suppression,  although drug resistance is still an unsolved problem that may dramatically reduce therapeutic options for this population. Faculty | Today, most people living with HIV (PLWH) with access to ART successfully achieve virological suppression,  although drug resistance is still an unsolved problem that may dramatically reduce therapeutic options for this population. Faculty | Today, most people living with HIV (PLWH) with access to ART successfully achieve virological suppression,  although drug resistance is still an unsolved problem that may dramatically reduce therapeutic options for this population. Faculty | Today, most people living with HIV (PLWH) with access to ART successfully achieve virological suppression,  although drug resistance is still an unsolved problem that may dramatically reduce therapeutic options for this population. Faculty | Today, most people living with HIV (PLWH) with access to ART successfully achieve virological suppression,  although drug resistance is still an unsolved problem that may dramatically reduce therapeutic options for this population. Faculty | Today, most people living with HIV (PLWH) with access to ART successfully achieve virological suppression,  although drug resistance is still an unsolved problem that may dramatically reduce therapeutic options for this population. Faculty | Today, most people living with HIV (PLWH) with access to ART successfully achieve virological suppression,  although drug resistance is still an unsolved problem that may dramatically reduce therapeutic options for this population. Faculty | Today, most people living with HIV (PLWH) with access to ART successfully achieve virological suppression,  although drug resistance is still an unsolved problem that may dramatically reduce therapeutic options for this population. Faculty | Today, most people living with HIV (PLWH) with access to ART successfully achieve virological suppression,  although drug resistance is still an unsolved problem that may dramatically reduce therapeutic options for this population. Faculty | Today, most people living with HIV (PLWH) with access to ART successfully achieve virological suppression,  although drug resistance is still an unsolved problem that may dramatically reduce therapeutic options for this population.

Faculty | 2nd PRESTIGIO Registry meetING on HIV multidrug...

  • Daniele Armenia, Saint Camillus International University of Health Sciences, Roma;
  • Stefano Bonora, Ospedale Amedeo di Savoia, Università degli Studi di Torino;
  • Andrea Calcagno, Ospedale Amedeo di Savoia, Università degli Studi di Torino;
  • Leonardo Calza, A.O.U. Policlinico S. Orsola-Malpighi, Bologna;
  • Elisabetta Carini, IRCCS Ospedale San Raffaele, Milano;
  • Antonella Castagna, IRCCS Ospedale San Raffaele Università Vita - Salute, Milano;
  • Anna Maria Cattelan, Azienda Ospedale Università di Padova;
  • Giovanni Cenderello, Azienda Socio Sanitaria Ligure 1, Sanremo;
  •  Adriana Cervo, Azienda Ospedaliero - Universitaria Policlinico di Modena;
  • Tommaso Clemente, Università Vita- Salute San Raffaele, Milano;
  • Laura Comi, ASST Papa Giovanni XXIII, Bergamo;
  • Mirko Compagno, Policlinico Tor Vergata, Roma;
  • Giuseppe V. De Socio, Azienda Ospedaliera di Perugia;
  • Steven Deeks, San Francisco General Hospital, University of California, San Francisco (USA);
  • Antonio Di Biagio, Ospedale Policlinico S.Martino, IRCCS, Università degli Studi di Genova;
  • Massimiliano Fabbiani, A.O.U. Senese - Università degli Studi di Siena;
  • Marta Fiscon, Azienda Ulss 9 Scaligera, Verona;
  • Emanuele Focà, Università degli Studi di Brescia ASST Spedali Civili di Brescia;
  • Roberta Gagliardini, INMI Lazzaro Spallanzani IRCCS, Roma;
  • Andrea Galli, IRCCS Ospedale San Raffaele, Milano;
  • Andrea Giacomelli, ASST Fatebenefratelli Sacco Ospedale Luigi Sacco, Milano;
  • Giovanni Guaraldi, Azienda Ospedaliero - Universitaria Policlinico di Modena, Università degli Studi di Modena e Reggio Emilia, Modena;
  • Filippo Lagi, Azienda Ospedaliero-Universitaria Careggi, Firenze;
  • Riccardo Lolatto, IRCCS Ospedale San Raffaele, Milano;
  • Giulia Marchetti, ASST Santi Paolo e Carlo, Università degli Studi di Milano;
  • Maria Mazzitelli, Azienda Ospedale Università di Padova;
  • Rebecka Papaioannu Borjesson, IRCCS Ospedale San Raffaele, Milano;
  • Stefano Rusconi, ASST Ovest Milanese, Ospedale Civile di Legnano, Università degli Studi di Milano;
  • Francesco Saladini, Università degli Studi di Siena;
  • Pierluigi Francesco Salvo, Università Cattolica del Sacro Cuore, Roma;
  • Maria Santoro, Università degli Studi di Roma Tor Vergata, Roma;
  • Vincenzo Spagnuolo, IRCCS Ospedale San Raffaele, Milano;
  • Anne Marie J. Wensing, University Medical Center, Utrecht (NL);
  • Maurizio Zazzi, Università degli Studi di Siena.
Faculty

Today, most people living with HIV (PLWH) with access to ART successfully achieve virological suppression,  although drug resistance is still an unsolved problem that may dramatically reduce therapeutic options for this population.

According to more recent Italian epidemiological data, the prevalence of multidrug resistance - MDR - [defined as at least one major resistant mutation in at least three different drug classes among NRTIs, NNRTIs, PIs and integrase strand transfer inhibitors (INSTIs)] among ART-experienced subjects with HIV was estimated at approximately 9% in the period 2011–2018. Individuals with multidrug-resistant (MDR) strains are usually characterized by a complex clinical history with previous or current uncontrolled viral replication, determining adaptive immune response depletion and occurrence of opportunistic infections. 

PRESTIGIO Registry, the observational, prospective, multicentre study, serves as a basis for evaluating the long-term effectiveness of antiretroviral therapies, the evolution of genotypic and phenotypic susceptibility to antiretroviral drugs, (particularly novel drugs being developed for highly treatment experienced patients – HTE - often harbouring multidrug resistant virus), the determinants of clinical outcomes including virological/immunological/inflammatory markers, and the incidence of AIDS related conditions and comorbidities.

This 2nd National Registry Meeting (RING)  is designed as a forum involving the PRESTIGIO Network of specialists as well as basic scientists and clinicians experienced in the management of this fragile population: the program  will include some key lectures hold by experts in the field interspersed with plenary discussion groups on challenging clinical experiences, so as to improve interaction and participation among attendees.

  • Daniele Armenia, Saint Camillus International University of Health Sciences, Roma;
  • Stefano Bonora, Ospedale Amedeo di Savoia, Università degli Studi di Torino;
  • Andrea Calcagno, Ospedale Amedeo di Savoia, Università degli Studi di Torino;
  • Leonardo Calza, A.O.U. Policlinico S. Orsola-Malpighi, Bologna;
  • Elisabetta Carini, IRCCS Ospedale San Raffaele, Milano;
  • Antonella Castagna, IRCCS Ospedale San Raffaele Università Vita - Salute, Milano;
  • Anna Maria Cattelan, Azienda Ospedale Università di Padova;
  • Giovanni Cenderello, Azienda Socio Sanitaria Ligure 1, Sanremo;
  •  Adriana Cervo, Azienda Ospedaliero - Universitaria Policlinico di Modena;
  • Tommaso Clemente, Università Vita- Salute San Raffaele, Milano;
  • Laura Comi, ASST Papa Giovanni XXIII, Bergamo;
  • Mirko Compagno, Policlinico Tor Vergata, Roma;
  • Giuseppe V. De Socio, Azienda Ospedaliera di Perugia;
  • Steven Deeks, San Francisco General Hospital, University of California, San Francisco (USA);
  • Antonio Di Biagio, Ospedale Policlinico S.Martino, IRCCS, Università degli Studi di Genova;
  • Massimiliano Fabbiani, A.O.U. Senese - Università degli Studi di Siena;
  • Marta Fiscon, Azienda Ulss 9 Scaligera, Verona;
  • Emanuele Focà, Università degli Studi di Brescia ASST Spedali Civili di Brescia;
  • Roberta Gagliardini, INMI Lazzaro Spallanzani IRCCS, Roma;
  • Andrea Galli, IRCCS Ospedale San Raffaele, Milano;
  • Andrea Giacomelli, ASST Fatebenefratelli Sacco Ospedale Luigi Sacco, Milano;
  • Giovanni Guaraldi, Azienda Ospedaliero - Universitaria Policlinico di Modena, Università degli Studi di Modena e Reggio Emilia, Modena;
  • Filippo Lagi, Azienda Ospedaliero-Universitaria Careggi, Firenze;
  • Riccardo Lolatto, IRCCS Ospedale San Raffaele, Milano;
  • Giulia Marchetti, ASST Santi Paolo e Carlo, Università degli Studi di Milano;
  • Maria Mazzitelli, Azienda Ospedale Università di Padova;
  • Rebecka Papaioannu Borjesson, IRCCS Ospedale San Raffaele, Milano;
  • Stefano Rusconi, ASST Ovest Milanese, Ospedale Civile di Legnano, Università degli Studi di Milano;
  • Francesco Saladini, Università degli Studi di Siena;
  • Pierluigi Francesco Salvo, Università Cattolica del Sacro Cuore, Roma;
  • Maria Santoro, Università degli Studi di Roma Tor Vergata, Roma;
  • Vincenzo Spagnuolo, IRCCS Ospedale San Raffaele, Milano;
  • Anne Marie J. Wensing, University Medical Center, Utrecht (NL);
  • Maurizio Zazzi, Università degli Studi di Siena.
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